骨髓转移癌82例诊断分析

目的：探讨骨髓转移癌（MCBM）的发病机制及临床与血液学特征，以提高诊断水平。方法：回顾分析82例MCBM患者的临床表现、X线检查、实验室检查、血象与骨髓象等资料。结果：82例MCBM患者中。临床表现以贫血（70．7％）、骨痛（57.3％）、发热（37．8％）及出血（25．6％）最常见。82例骨髓涂片均找到MCBM细胞，其中43例（52．4％）找到原发肿瘤，以肺癌（19．5％）、乳腺癌（10．9％）和胃肠道癌（4．9％）最多见。结论：临床上，当患者出现不明原因的贫血、骨痛、发热及（或）出血等症状时，应考虑MCBM可能，可作骨髓穿刺或骨髓活检，寻找原发癌的来源。

Diagnostic analysis of 82 cases of bone marrow metastatic cancer

Objective To investigate the pathogenesis and the clinical and hematological characteristics of bone marrow metastatic cancer for the purpose of enhancing its diagnostic level. Methods The clinical manifestations, X-ray examination, laboratory tests, blood and bone marrow pictures were reviewed for diagnostic analysis in 82 cases of bone marrow metastatic cancer. Results Anaemia （70.7%）, bone pain （57.3%）, fever （37.8%） and hemorrhage （25.6 percent） were the most frequently seen clinical manifestations. Metastatic cancer ceils were found in the bone marrow smear of all the 82 cases. Primary cancer was identified in 43 cases （52.4%）, including lung cancer （19.5 %）, breast cancer （10.9%） and gastrointestinal cancer （4.9%）. Conclusions Bone marrow metastatic cancer should be considered as a possibility when anemia, bone pain and fever of unknown origin occur, and bone marrow aspiration or biopsy should be performed timely to find out the source of primary cancer