Abstract: | A sixty-six-year-old woman has had numerous macules all over her body for a year without any systemic involvements. Plasma cells had infiltrated into the dermis and perivascular region, but showed no mitotic figures nor atypicalities. Laboratory examinations for Bence Jones protein, serum gammaglobulin, and immunoglobulins demonstrated no abnormal findings. The surface markers of the plasma cells were polyclonal; they were stained by anti IgA, IgG, IgM, kappa, and lambda. We consider this case not to be one of a true tumor but one of rather benign reactive proliferation of plasma cells in the skin, although its etiology is unclear. |