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乳腺癌还氧合酶-2表达的研究现状
引用本文:姚建国,陈莉. 乳腺癌还氧合酶-2表达的研究现状[J]. 国外医学(肿瘤学分册), 2007, 0(5)
作者姓名:姚建国  陈莉
作者单位:南通大学附属南通第三医院病理科,南通大学附属南通第三医院病理科
摘    要:还氧合酶-2(COX-2)过表达与很多肿瘤发生发展有关。最近研究显示COX-2在乳腺癌细胞株和组织标本中表达增加,提示COX-2可能直接参与乳腺癌的形成,并且与预后有关。因此,应用COX-2抑制剂治疗乳腺癌成为目前的研究热点。

关 键 词:乳腺肿瘤  还氧合酶-2

Current research status of cyclooxygenase-2 expression in breast carcinoma
YAO Jian-guo. Current research status of cyclooxygenase-2 expression in breast carcinoma[J]. Foreign Medical Sciences (Cancer Section), 2007, 0(5)
Authors:YAO Jian-guo
Affiliation:YAO Jian-guo Department of Pathology,the Nantong Third Hospital of Nantong University,Nantong 226006,China
Abstract:Overexpression of cyclooxygenase-2(COX-2)is related to carcinogenesis and progression of many human carcinomas.Recent researches show that COX-2 expression is increased in breast cancer cell lines and specimens,which indicates that COX-2 may be directly involved with mammary carcinogenesis and is associated with the prognosis of breast cancer.Thus the research of COX-2 inhibitors for treating breast cancer becomes a hot issue at present.
Keywords:Breast neoplasms  Cyclooxygenase-2
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