| CCL19/21-CCR7生物学轴与肿瘤转移 |
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| 引用本文： | 杨银龙,欧周罗,邵志敏. CCL19/21-CCR7生物学轴与肿瘤转移[J]. 国外医学(肿瘤学分册), 2006, 0(8) |
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| 作者姓名： | 杨银龙 欧周罗 邵志敏 |
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| 作者单位： | 复旦大学附属肿瘤医院乳腺癌研究所，复旦大学附属肿瘤医院乳腺癌研究所，复旦大学附属肿瘤医院乳腺癌研究所 |
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| 摘 要： | 肿瘤转移有其选择性和特异性,不同组织来源的肿瘤易向某些特定的组织和器官如淋巴结、肺、肝、骨等转移,但人们对其机制知之甚少。近年来,发现不少趋化因子及其受体在肿瘤的转移中扮演重要角色。现就CCL19/21-CCR7生物学轴在肿瘤转移中的作用作一综述。
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| 关 键 词： | 炎症趋化因子类 受体 趋化因子 肿瘤转移 |
CCL19/21-CCR7 biological axis and cancer metastasis |
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| YANG Yin-long OU Zhou-luo SHAO Zhi- min,Breast Cancer Institute,Cancer Hospital,Fudan University,Shanghai ,China. CCL19/21-CCR7 biological axis and cancer metastasis[J]. Foreign Medical Sciences (Cancer Section), 2006, 0(8) |
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| Authors: | YANG Yin-long OU Zhou-luo SHAO Zhi- min Breast Cancer Institute Cancer Hospital Fudan University Shanghai China |
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| Affiliation: | YANG Yin-long OU Zhou-luo SHAO Zhi- min,Breast Cancer Institute,Cancer Hospital,Fudan University,Shanghai 200032,China |
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| Abstract: | Cancer metastasis presents a highly non-random and organ-selective process.Certain tumors show a metastatic tendency towards specific organs,such as lymph nodes,lungs,livers,bone, and so on.However,we don't have much information of theirt mechanisms.Recently,researches find chemokines and their receptors play important roles in tumors organ-selective metastasis.This article will review the roles of CCL19/21-CCR7 biological axis in cancer metastasis. |
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| Keywords: | Chemokines Receotors chemokines Neoplasm metastasis |
| 本文献已被 CNKI 等数据库收录！ |
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