呼吸内科518例住院患者细菌耐药情况调查分析

目的调查我院呼吸内科住院患者病原学检测及药敏情况，并分析细菌耐药原因，为指导临床合理用药提供依据。方法采用回顾性调查研究方法，对呼吸内科518例住院病历的主要临床诊断、病原学检测及药敏情况等进行统计分析。结果呼吸内科住院患者以感染性疾病为主，病原学送检率为75．78％，阳性率为10．43％，主要致病菌为肺炎链球菌、酵母样真菌和流感嗜血杆菌，肺炎链球菌和肺炎克雷伯菌对多种抗菌药物耐药。385例做细菌培养＋药敏，送检率75．78％，其中阳性53例，阳性率为10．43％。413例患者好转，60例治愈，22例死亡，18例未愈，其他5例上级医院治疗。结论我院呼吸内科病原学送检率较高，阳性率较低，其中肺炎链球菌和肺炎克雷伯菌耐药形势严峻，应进一步提高送检标本的质量，合理使用抗菌药物，尽量改善耐药现状。

Analysis of the pathogenic bacteria's drug-resistance condition in 518 in-patients in respiratory medical department

Objective To investigate the detection of pathogens and susceptibility conditions and analyze its drug-resistance reason in-patients in the respiratory medical department for providing evidence in order to guide the rational administration of clinics. Methods Five hundred and eighteen medical records of the respiratory medical department had been investigated by retrospective review method. The main clinical diagnosis, the detection of pathogens and susceptibility conditions were analyzed and counted. Results Infectious diseases were the main clin-ical diagnosis of the in-patients of the respiratory medical department. The pathogens' submission rate was 75.29% and the rate of masculine was 13. 77% . The main pathogenic bacteria were Streptococcus Pneumoniae, Yeast-like fungi and Hemophilus influenzae. Streptococcus Pneumoniae and Klebsiella Pneumoniae were drug fast to many anti-biotics. Conclusions The pathogens' submission rate in our hospital is high and the rate of masculine is low. The conditions of the drug-resistance of Streptococcus Pneumoniae and Klebsiella Pneumoniae is very serious. We should improve the sample's quality and use antibacterials rationally in order to improve the drug-resistance conditions.