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应用ROC曲线评价CEA、CYFRA21-1、SCC对非小细胞肺癌的诊断价值
引用本文:罗疏薇,欧春萍,张莉萍,陈宏础. 应用ROC曲线评价CEA、CYFRA21-1、SCC对非小细胞肺癌的诊断价值[J]. 重庆医学, 2011, 40(3): 250-252,255. DOI: 10.3969/j.issn.1671-8348.2011.03.017
作者姓名:罗疏薇  欧春萍  张莉萍  陈宏础
作者单位:重庆医科大学附属第一医院检验科,400016;重庆医科大学附属第一医院检验科,400016;重庆医科大学附属第一医院检验科,400016;重庆医科大学附属第一医院检验科,400016
摘    要:目的 探讨癌胚抗原(CEA)、细胞角蛋白19片段抗原(CYFRA21-1)、鳞癌相关抗原(SCC)对非小细胞肺癌(NSCLC)的诊断价值并找出此3种肿瘤标志物(TM)对NSCLC的临床诊断界值(cut off 值).方法 对99例NSCLC患者、50例肺部良性疾病患者以及50例健康体检者血清中CEA、CYFRA21-1...

关 键 词:ROC曲线  癌胚抗原  角蛋白质类  cut off值  鳞状细胞癌相关抗原

Application of ROC curve to evaluate CEA,CYFRA21-1,SCC to non-small cell lung cancer diagnosis value
Luo Shuwei,Ou Chunping,Zhang Liping,Chen Hongchu. Application of ROC curve to evaluate CEA,CYFRA21-1,SCC to non-small cell lung cancer diagnosis value[J]. Chongqing Medical Journal, 2011, 40(3): 250-252,255. DOI: 10.3969/j.issn.1671-8348.2011.03.017
Authors:Luo Shuwei  Ou Chunping  Zhang Liping  Chen Hongchu
Affiliation:Luo Shuwei,Ou Chunping,Zhang Liping,Chen Hongchu(Department of Laboratory,the First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
Abstract:Objective To investigate the diagnosis value of CEA,CYFRA21-1 and SCC in non-small cell lung cance(NSCLC),and discover the clinical cut off point of them.Methods Serum concentration of CEA,CYFRA2l-1 and SCC was measured in 99 patients with NSCLC,50 patients with benign lung disease and 50 healthy subjects.CEA and CYFRA21-1 were measured by electrochemiluminescence immunoassays on the Roche Eleesys170,and SCC was measured by ehemiluminesent micmparticle Immmmassay on ARCHITECT i2000SR.Used ROC curve to analy...
Keywords:ROC curve  carcinoembryonic antigen  keratins  cut off point  SCC  
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