| Pak1基因在乳腺癌组织中的表达及临床意义 |
| |
| 引用本文： | 李秋云,施俊义,盛湲.Pak1基因在乳腺癌组织中的表达及临床意义[J].重庆医学,2011,40(7):646-649,后插3. |
| |
| 作者姓名： | 李秋云 施俊义 盛湲 |
| |
| 作者单位： | 第二军医大学附属长海医院乳腺外科,上海,200433 |
| |
| 摘 要： | 目的 研究乳腺肿瘤组织中p21激活激酶1(Pak1) mRNA及其蛋白在正常乳腺组织、良性乳腺肿瘤组织、乳腺癌组织中表达的情况,探讨Pak1与淋巴结转移、雌激素受体(ER)、孕激素受体(PR)及癌胚表达抗原(CerbB-2)表达的关系.方法 采用实时荧光定量RT-PCR技术检测35例乳腺癌和20例乳腺良性病变、15例远...
|
| 关 键 词： | 乳腺肿瘤 逆转录聚合酶链反应 免疫组织化学 p21活化激酶类 |
Expression of Pak1 gene in breast carcinoma and its clinical significance |
| |
| Li Qiuyun,Shi Junyi,Sheng Yuan.Expression of Pak1 gene in breast carcinoma and its clinical significance[J].Chongqing Medical Journal,2011,40(7):646-649,后插3. |
| |
| Authors: | Li Qiuyun Shi Junyi Sheng Yuan |
| |
| Institution: | Li Qiuyun,Shi Junyi,Sheng Yuan(Department of Breast Surgery,Changhai Hospital Affiliated to Second Military Medical University,Shanghai 200433,China) |
| |
| Abstract: | Objective To investigate mRNA and protein expression of Pak1 gene in normal breast tissue,benign mammary lesions and breast carcinoma,to explore whether the expression of Pak1gene in breast carcinoma is related to lymph node metastases,the level of ER,PR and CerbB-2 or not.Methods The mRNA expression of Pak1 gene was detected in 35 cases of breast carcinoma,20 cases of benign mammary lesions and 15 cases of normal breast tissue by fluorescent real-time RT-PCR;35 cases of paraffin-embedded specimens of breas... |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
