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360例急诊呼吸困难患者氨基末端脑钠肽前体检测的意义
引用本文:张玉梅,李俊,唐忠银. 360例急诊呼吸困难患者氨基末端脑钠肽前体检测的意义[J]. 重庆医学, 2011, 40(9): 874-875,877. DOI: 10.3969/j.issn.1671-8348.2011.09.017
作者姓名:张玉梅  李俊  唐忠银
作者单位:广西壮族自治区桂林市中西医结合医院急诊科,541004;广西壮族自治区桂林市中西医结合医院急诊科,541004;广西壮族自治区桂林市中西医结合医院急诊科,541004
摘    要:目的评价快速测定氨基末端脑钠肽前体(NT-proBNP)对急诊呼吸困难患者病因鉴别诊断的应用价值。方法选取以呼吸困难为主要症状的患者360例,分为心源性呼吸困难(A组,172例)和非心源性呼吸困难(B组,188例)两组,分别测定患者血浆NT-proBNP浓度,对比分析心力衰竭所致呼吸困难和非心力衰竭所致呼吸困难患者的血浆NT-proBNP浓度。结果 A组患者NT-proBNP浓度明显高于B组患者(P<0.01);NT-proBNP与左室射血分数(LVEF)呈负相关。A组NT-proBNP浓度在不同年龄组间差异有统计学意义。A组患者不同心功能分级血浆NT-proBNP浓度差异有统计学意义(P<0.05)。结论床边快速测定血浆NT-proBNP浓度对急诊以呼吸困难为主要表现的心力衰竭患者病因鉴别诊断和处理具有较高的应用价值。

关 键 词:呼吸困难  心力衰竭  氨基末端脑钠肽前体

Clinical analysis of N-terminal pro-brain natriuretic peptide of 360 patients with acute dyspnea
Zhang Yumei,Li Jun,Tang Zhongying. Clinical analysis of N-terminal pro-brain natriuretic peptide of 360 patients with acute dyspnea[J]. Chongqing Medical Journal, 2011, 40(9): 874-875,877. DOI: 10.3969/j.issn.1671-8348.2011.09.017
Authors:Zhang Yumei  Li Jun  Tang Zhongying
Affiliation:Zhang Yumei,Li Jun,Tang Zhongying(Department of Emergency,Guilin Hospital of Integrated Traditional and Western Medicine,Guilin,Guangxi 541004,China)
Abstract:Objective To evaluate the applied value of determining quickly plasma level of N-terminal pro-brain natriuretic peptide(NT-proBNP) in the differential diagnosis of acute dyspnea.Methods Three hundred and sixty patients with dyspnea were divided into two groups:cardiac dyspnea group(172 cases)and non-cardiac dyspnea group(188 cases).Plasma NT-proBNP levels were determined.Plasma NT-proBNP levels of the patients with dyspnea induced by heart failure and non-heart failure were analyzed comparatively.Results Th...
Keywords:dyspnea  heart failure  N-terminal pro-brain natriuretic peptide  
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