| 良好的HLA配型可改善PRA高敏受者的移植效果 |
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| 引用本文： | 于立新,肖露露,白喜文.良好的HLA配型可改善PRA高敏受者的移植效果[J].南方医科大学学报,1997(4). |
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| 作者姓名： | 于立新 肖露露 白喜文 |
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| 作者单位： | 南方医院肾移植中心!广州市510515(于立新，白喜文)，广州器官移植配型中心!广州市510095(肖露露) |
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| 摘 要： | 报告5例淋巴细胞群体反应抗体（PRA）为48％～76％，采用理想的HLA配型，供受者间HLA－A、B、DR位点在3～5个抗原相合情况下进行移植，术后3例发生急性排斥反应，经用甲基强的松龙及OKT3冲击治疗后排斥逆转。5例全部成功，术后均获得随访，人／肾存活9个月～2年4例，3年半1例。讨论了PRA高敏感对移植物的影响，良好的HLA配型对移植效果的影响。
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| 关 键 词： | 肾移植术 人类白细胞抗原 群体反应 抗体 |
Good HLA matching can improved the transplant results on the PRA hypersensitivity recipient |
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| Yu Lixin,Xiao Lulu,Bai Xiwen.Good HLA matching can improved the transplant results on the PRA hypersensitivity recipient[J].Journal of Southern Medical University,1997(4). |
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| Authors: | Yu Lixin Xiao Lulu Bai Xiwen |
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| Abstract: | Five patients with PRA positive rat reached 48~76% had accepted successful kidney transplanta-tion in our department, under good HLA matching that doners and recipients had 3~5 uniform situs onHLA-A,B,DR site. 3 cases had accured acute rejection after operation,but recovered by using methylpred-nisolone and OKT_3. They all followed up,the patient/kidney has survived for 9 months to 2 years in 4 cas-es. 3. 5 years in 1 case. In this report,we will discuss the influence of hypersensitivity of PRA on the graftand the improvement of transplant result by HLA matching on these patients. |
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| Keywords: | kidney transplantation PRA HLA |
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