| 针药结合对Graves′眼病患者血清眼外肌抗体依赖细胞介导的细胞毒作用 |
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| 引用本文： | 孙克兴,魏建子,王静,庞熠,楼建华,何金森. 针药结合对Graves′眼病患者血清眼外肌抗体依赖细胞介导的细胞毒作用[J]. 上海中医药杂志, 2001, 35(8): 38-40 |
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| 作者姓名： | 孙克兴 魏建子 王静 庞熠 楼建华 何金森 |
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| 作者单位： | 上海中医药大学,上海,200032 |
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| 基金项目： | 上海市教委青年基金(99QB75) |
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| 摘 要： | 为探讨针药结合治疗Graves′眼病（GO）的免疫学机理,54例GO患者随机分为治疗Ⅰ组、治疗Ⅱ组和对照组各18例,测定治疗前后患者血清对有眼外肌抗体依赖细胞介导的细胞毒（ADCC)航血清抗眼肌膜抗体（EMAb）的水平。结果：治疗后患者血清对眼外肌的ADCC作用较治疗前明显降低,且治疗Ⅱ组低于对照组（P＜0．05）;血清EMAb水平在针刺治疗后明显降低（P＜0．05,P＜0．001）;针刺Ⅱ组水平低于Ⅰ组和对照组（P＜0．01,P＜0．001）。提示针药结合治疗Graves′眼病的眼肌损伤可能与降低EMAb,减轻对眼外肌的ADCC有关。
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| 关 键 词： | Garaves′眼病 针药结合 抗体依赖细胞介导 细胞毒 抗眼肌膜抗体 |
| 文章编号： | 1007-1334(2001)08-0038-03 |
| 修稿时间： | 2001-02-21 |
Effects of Acupuncture and Medicine on Serum Antibody-Dependent Cell- Mediated Cytotoxicity in Ocular Lateral Muscle of Patient with Graves' Ophthalmopathy |
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| SUN Ke-xing WEI Jian-zi WANG Jing PANG Yi LOU Jian hua Supervisor:"HE Jin senShanghai University of Traditional Chinese Medicine. Effects of Acupuncture and Medicine on Serum Antibody-Dependent Cell- Mediated Cytotoxicity in Ocular Lateral Muscle of Patient with Graves' Ophthalmopathy[J]. Shanghai Journal of Traditional Chinese Medicine, 2001, 35(8): 38-40 |
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| Authors: | SUN Ke-xing WEI Jian-zi WANG Jing PANG Yi LOU Jian hua Supervisor:" HE Jin senShanghai University of Traditional Chinese Medicine |
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| Affiliation: | SUN Ke-xing WEI Jian-zi WANG Jing PANG Yi LOU Jian hua Supervisor:*"HE Jin senShanghai University of Traditional Chinese Medicine |
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