| 注射用七叶皂苷钠中七叶皂苷钠A和B的含量测定 |
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| 引用本文： | 沈芊,曾艳,王淑洁,王育琴.注射用七叶皂苷钠中七叶皂苷钠A和B的含量测定[J].中成药,2004,26(4):286-288. |
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| 作者姓名： | 沈芊 曾艳 王淑洁 王育琴 |
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| 作者单位： | 首都医科大学宣武医院药剂科,北京,100053 |
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| 摘 要： | 目的:对北京市场上的注射用七叶皂苷钠进行含量测定,为控制产品质量提供依据.方法:依据国家标准,采用酸碱中和滴定法测定注射用七叶皂苷钠中总皂苷含量,同时采用高效液相色谱法测定七叶皂苷钠A和七叶皂苷钠B的含量.结果:不同厂家的样品中总皂苷含量均符合国家标准规定;而七叶皂苷钠A和七叶皂苷钠B的含量存在差别.结论:国家标准实施后,注射用七叶皂苷钠产品中七叶皂苷钠A和七叶皂苷钠B的含量有较大提高.
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| 关 键 词： | 七叶皂苷钠 |
| 文章编号： | 1001-1528(2004)04-0286-03 |
Comparative study on quality of Sodium Aescinate for injection of different manufacturer |
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| SHEN Qian,ZENG Yan,WANG Shu jie,WANG Yu qin.Comparative study on quality of Sodium Aescinate for injection of different manufacturer[J].Chinese Traditional Patent Medicine,2004,26(4):286-288. |
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| Authors: | SHEN Qian ZENG Yan WANG Shu jie WANG Yu qin |
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| Abstract: | AIM: To determine the contents of Sodum Aescinate for Injection in Beijing market in order to provide the basis for quanlity control. METHODS: According to national criterion, total aescinate is determinted by acid base titration. The contents of sodium aescinate A and sodium aescinate B in products are determined by HPLC. RESULTS: The total aescinate content in samples of the different manufactures are accord with national criterion, but the contents of sodium aescinate A and sodium aescinate B in products are different. CONCLUSION: After national criterion was carried into practice, the contents of sodium aescinate A and sodium aescinate B in products were up to standard. |
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| Keywords: | HPLC |
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