磁共振弥散加权成像对胰腺癌与慢性肿块型胰腺炎的鉴别诊断价值 |
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引用本文: | 陆靖,陆建平,王飞,王莉,刘崎,何新红,汪剑,王蓓,吴轶娜.磁共振弥散加权成像对胰腺癌与慢性肿块型胰腺炎的鉴别诊断价值[J].中华胰腺病杂志,2008,8(3). |
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作者姓名: | 陆靖 陆建平 王飞 王莉 刘崎 何新红 汪剑 王蓓 吴轶娜 |
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作者单位: | 第二军医大学长海医院放射科, 上海,200433 |
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摘 要: | 目的 比较磁共振弥散加权成像(diffusion-weighted imaging,DWI)对胰腺癌与慢性肿块型胰腺炎的鉴别能力.方法 对38例胰腺癌、9例肿块型CP、15例正常胰腺行DWI.在x、Y、Z轴3个方向上选择3个不同弥散系数(b=0、500、1 000 s/mm2)进行扫描,共行2次DWI.根据表观弥散系数(apparent diffusion coefficient,ADC)图像测量ADC值.结果 38例胰腺癌平均ADC值为(1.411±0.101)×10m-3mm2/s,9例肿块型CP的平均ADC值为(1.053±0.113)×10-3mm2/s,15例正常胰腺平均ADC值为(1.245±0.112)×10-3mm2/s,两两比较均有统计学意义(P<0.05).结论 DWI可对胰腺癌与肿块型CP进行鉴别诊断,具有较大的临床意义.
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关 键 词: | 胰腺疾病 磁共振成像 弥散 b值 表观弥散系数 |
The value of DWI in diagnosis and differential diagnosis of pancreatic carcinoma from chronic lump type pancreatitis |
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Authors: | LU Jing LU Jian-ping WANG Fei WANG Li LIU Qi HE Xin-hong WANG Jian WANG Bei WU Yi-na |
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Abstract: | Objective To evaluate the ability of diffusion-weighted imaging (DWI)in differentiating pancreatic carcinoma from chronic lump type pancreatitis. Methods Totally 38 cases of pancreatic cancer, 9 cases of chronic lump type pancreatitis, 15 cases of normal patients underwent DWI. DWI with b value=0, 500, 1 000 s/mm2 was performed twice. Apparent diffusion coefficient (ADC) was measured by analysis of imagines of ADC. Results The mean ADC value of 38 subjects with pancreatic carcinoma was (1.411± 0.101)×10-3 mm2/sec, the mean ADC value of 9 subjects with lump type pancreatitis was (1.053±0.113) ×10-3 mm2/sec, and the mean ADC value of normal pancreas subjects was (1.245±0.112)×10-3 mm2/s. The difference between the three groups were statistically significant (P<0.05). Conclusions DWI may have the clinical potential to differentiate chronic lump type pancreatitis from pancreatic carcinoma. |
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Keywords: | Pancreatic disease Diffusion magnetic resonance imaging b value Apparent diffusion coefficient |
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