| 献血员中人类T淋巴细胞白血病病毒感染的检测 |
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| 引用本文： | 张国忠,薛国章,罗斌,林丽容,田萍萍,林金煌,陈平.献血员中人类T淋巴细胞白血病病毒感染的检测[J].中华检验医学杂志,2001,24(3):144-145. |
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| 作者姓名： | 张国忠 薛国章 罗斌 林丽容 田萍萍 林金煌 陈平 |
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| 作者单位： | 福建省莆田市中心血站检验科, |
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| 摘 要： | 目的：了解人类T淋巴细胞白血病病毒（HTLV）流行献血员中HTLV感染情况，方法：对福建莆田沿海地区献血员2339份血标本，以国产双抗原夹心法进行酶联免疫吸附法（ELISA）试剂盒的筛选，对ELISA阳性血清均用蛋白印迹试验和(或）聚合酶链反应（PCR）结合序列测定进行确证。结果：2339份献血员血标本中，确证阳性9份，均为HTLV－Ⅰ感染，结论福建莆田沿海地区献血员中，HTLV感染率为0．38％。
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| 关 键 词： | HTLV－Ⅰ感染 供血者 酶联免疫吸附测定 ELISA |
| 修稿时间： | 2000年9月25日 |
Prevalence of human T lymphotropic virus infection among blood donors |
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| ZHANG Guozhong,XUE Guozhang,LUO Bin,et al..Prevalence of human T lymphotropic virus infection among blood donors[J].Chinese Journal of Laboratory Medicine,2001,24(3):144-145. |
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| Authors: | ZHANG Guozhong XUE Guozhang LUO Bin |
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| Institution: | ZHANG Guozhong,XUE Guozhang,LUO Bin,et al. Putian Blood Center,Fujian 351100,China |
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| Abstract: | Objective To obtain the prevalence data on human T Lymphotropic virus (HTLV) infection in 2 339 blood donors of an endemic coastal region of Fujian, China. Methods Serum antibodies to HTLV in the donors were detected by a home made double antigen sandwitch ELISA kit. All the ELISA positive samples were further confirmed by Western blot (WB) and/or polymerase chain reaction (PCR) combined with sequencing. Results Nine samples were confirmed as HTLV 1 infection among the 2 339 donors. A man whose wife is one of the nine was also detected to infect by WB and PCR. Conclusion The prevalence of HTLV infection was 0.38% in the endemic coastal region of Fujian, China. |
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