小剂量氧气持续雾化湿化降低人工气道患者肺部感染的临床研究

目的分析小剂量氧气持续雾化湿化对降低人工气道患者肺部感染的临床疗效,探讨临床降低人工气道患者肺部感染的有效方法。方法选择我院2008年5月至2013年5月住院患者人工气道患者148例,随机分为研究组和对照组,每组各74例。研究组采用持续小剂量氧气持续雾化湿化;对照组采用持续微量泵滴注气道湿化。观察比较两组气道湿化效果及对肺部感染情况的影响。结果研究组湿化效果显著优于对照组,研究组刺激性咳嗽、气道内痰痂形成、气道黏膜出血、痰培养阳性率均低于对照组(P<0.05),具有显著性差异;同对照组相比,气道开通前3 d,研究组痰培养阳性率无显著性差异(P>0.05),第5天、第7天、第14天,研究组痰培养阳性率显著降低(P<0.05)。结论采用小剂量氧气持续雾化湿化,可明显降低人工气道患者肺部感染的发生,为人工气道患者肺部感染的临床预防应用提供了有效方法。

Clinical Studies of Low-dose Continuous Oxygen Atomization Humidification Reduces Artificial Airway Infection in the

Objective To analyze low-dose continuous oxygen atomization humidification to reduce the clinical efficacy of artificial lung airway infection, clinically effective method to explore the artificial lung infections reduce the patient＇s airway. Methods Hospital from May 2008 to May 2013 inpatient artificial airway 148 cases of patients were randomly divided into study group and the control group, 74 cases in each group. Study group continued using continuous low-dose oxygen atomization humidification; the control group continued micro pump infusion airway humidification. Wet effect and impact on the lung infection in the two groups were observed and compared the airway. Results The study group was significantly wet effect than the control group, the study group irritating cough, sputum formation airway, airway mucosal bleeding, sputum culture positive rate than the control group（P〈0.05）, with a significant difference ; compared with the control group, three days before the airway open, study groups sputum culture positive rate was no significant difference（P〉0.05）, the first five days, the first seven days, day 14 of the study group sputum culture positive rate was significantly lower（P〈0.05）. Conclusion The use of small doses of oxygen continuous atomization humidification, can significantly reduce the artificial lung airway infection, provides an effective method for the artificial lung airway infection prevention clinical applications.