8536例健康体检者幽门螺杆菌血清尿素酶抗体阳性率分析

目的了解长沙地区健康体检者幽门螺杆菌血清尿素酶抗体阳性率情况。方法采用胶体金法检测8 536例健康体检者血清幽门螺杆菌尿素酶抗体。结果 8 536例健康体检者幽门螺杆菌血清尿素酶抗体阳性率为25.7%,男女幽门螺杆菌血清尿素酶抗体阳性率经χ2检验差异有统计学意义(P<0.05);各年龄组幽门螺杆菌血清尿素酶抗体阳性率经χ2检验差异亦有统计学意义(P<0.01),但并不随着年龄增大而增加。结论长沙地区幽门螺杆菌的高感染率及其高致病性应引起重视。

Analysis on Sero-prevalence of Urease Antibody in Helicobacter pylori Among 8,536 Healthy Examinees

Objective To study the sero-prevalence of urease antibody in Helicobacter pylori in healthy examinees in Changsha. Methods We detected the urease antibody of Helicobacter pylori in the sera of 8,536 healthy examinees by using colloidal gold method. Results Among 8,536 healthy examinees,the sero-prevalence of urease antibody in Helicobacter pylori was 25.7%.There were statistically significant differences in the sero-prevalence of urease antibody in Helicobacter pylori between males and females by χ2 test(P<0.05).The sero-prevalence of urease antibody in Helicobacter pylori in different age groups also had statistically significant difference by χ2 test(P<0.01),but the increase of sero-prevalence did not match the increase of ages. Conclusions Close attention should be paid to the prevalence and high pathogenicity of Helicobacter pylori in Changsha.