甲磺酸罗哌卡因致荨麻疹

1例42岁女性患者行右侧甲状腺次全切除术,术前心率80次/min,血压130/80 mm Hg(1 mm Hg=0.133 kPa)。采用利罗合剂(2%利多卡因10 ml+0.894%甲磺酸罗哌卡因10 ml)行双侧颈神经丛阻滞麻醉。10 min后患者胸部出现荨麻疹,心率110次/min,血压155/110 mm Hg,随后腹部与下肢均出现荨麻疹,心率125次/min,血压160/100 mm Hg。即刻给予吸氧,静脉注射地塞米松10 mg,5 min后荨麻疹有所减退。又肌内注射苯海拉明20 mg,5 min后心率95次/min,血压140/90 mm Hg,荨麻疹完全消失。

Urticaria induced by ropivacaine mesylate

An 42-year-old woman underwent right subtotal thyroidectomy.Preoperatively,her heart rate(HT) was 80 beats/min and blood pressure(BP) was 130/80 mm Hg.Bilateral cervical plexus block was performed with mixture of lidocaine and ropivacaine(2% lidocaine 10 ml+0.894% ropivacaine mesylate 10 ml).Ten minutes later,the patient developed urticaria on her chest,her HR was 110 beats/min and BP 150/110 mm Hg.Subsequently,the urticaria was appeared in abdomen and legs.Her HR was 125 beats/min and BP 160/100 mm Hg.Oxygen and IV dexamethasone 10 mg were given immediately.Five minutes later,her urticaria receded gradually.And IM diphenhydramine 20 mg was given.Five minutes later,her HR was 95 beats/min,BP was 140/90 mm Hg,and the urticaria disappeared completely.