脑梗死各种危险因素的相关性研究

目的 分析脑梗死患者的颈动脉内膜-中层厚度(IMT)、斑块性质与各种危险因素间的相关性.方法 选取我院神经内科住院治疗的脑梗死患者257例,对患者的年龄、高血压、吸烟、饮酒、血糖、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、颈动脉IMT及颈动脉斑块进行记录,使用统计学分析方法分析.结果 分析后发现,不同年龄阶段,IMT存在差异,各年龄段间两两比较,差异均有统计学意义(P＜0.05);患者IMT值与LDL之间:R=23.328、标准化系数=0.810(t=13.415、P＜0.05).颈动脉粥样硬化斑块与LDL的相关系数为:Sig=0.009,Exp(B)=4.758;与Fg的相关系数为:Sig=0.028,Exp(B)=0.999.结论 随着年龄的增长,IMT逐渐增厚,成为脑梗死的重要危险因素;血浆纤维蛋白原(Fg)是脑梗死的重要危险因素,具有相对独立性,对其进行干预,可以有效降低脑梗死发病率.

Correlation Study of Cerebral Infarction Risk Factors

Objective Analysis of cerebral infarction in patients with carotid artery intima-media thickness,plaque and various risk factors correlation.Methods In our hospital 257 cases of patients with cerebral infarction neurological department of internal medicine in hospital,patient age,hypertension,smoking,drinking,glucose,TG,TC,LDL,HDL,IMT in carotid artery and carotid plaque were recorded,using statistical analysis methods analysis.Results Analysis of the results found,different ages,IMT existence difference,age compared,the differences were statistically significant(P<0.05);patients with IMT value and LDL:R=23.328,standardized cofficients beta=0.810(t=13.415,P<0.05).Carotid atherosclerotic plaque and coefficient correlation of LDL:Sig=0.009,Exp(B)=4.758;and Fg correlation coefficient was:Sig=0.028,Exp(B)=0.999.Conclusion With the increase of age,IMT thickened gradually,become an important risk factor of cerebral infarction;LDL and Fg was important risk factor of cerebral infarction,with relative independence,to intervene,can effectively reduce the incidence rate of cerebral infarction.