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Dipyridamole thallium-201 myocardial scintigraphy in coronary diagnosis; a comparison of methods with thallium-201 myocardial scintigraphy after ergometer stress
Authors:J Neuzner  P Kornecki  P Kremer  S Grebe  M Schlepper
Institution:Kerckhoff-Klinik der Max-Planck-Gesellschaft, Bad Nauheim.
Abstract:Two scintigraphic methods, resting dipyridamole and exercise thallium-201 myocardial perfusion imaging, to detect and localize coronary artery stenosis were compared in 32 patients suffering from coronary artery disease. The sensitivity of detecting a greater than 50% coronary stenosis was 94% for exercise thallium-201 perfusion imaging and 88% for dipyridamole thallium-201 perfusion imaging. The overall sensitivity and specificity of localizing a greater than 50% coronary stenosis by the two methods were also not significantly different. The results of the two scintigraphic methods were independent of the severity of coronary artery disease. Dipyridamole thallium-201 myocardial perfusion imaging provides a useful and safe alternative test for detecting and localizing coronary artery stenosis in patients unable to perform maximal exercise.
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