2006－2013年江苏省昆山市居民结直肠癌发病与死亡趋势分析

目的：结直肠癌是影响居民健康的主要癌症之一，且发病率呈现明显上升趋势。本研究探讨江苏省昆山市2006－2013年结直肠癌发病与死亡趋势。方法江苏省昆山市2006－2013年结直肠癌发病和死亡病例来源于昆山市肿瘤登记报告；计算结直肠癌粗发病（死亡）率与发病（死亡）的年龄标化率（age standardized rate，ASR）；使用平均年度变化百分比（annual percent change，APC）及其95％CI，评价结直肠癌发病率和死亡率在年份之间变化趋势。结果江苏省昆山市2006－2013年结直肠癌发病 ASR 在女性人群中呈明显上升趋势，APC＝2．3％，95％CI 为0．5％～4．2％；结直肠癌发病率总体变化趋势（APC＝0．6％，95％ CI 为－0．8％～1．9％）与男性人群（APC＝－0．8％，95％ CI 为－3.5％～1．5％）差异无统计学意义。昆山市2006－2013年结直肠癌死亡 ASR 在总体（APC ＝－5．3％，95％CI 为－9．0％～－1．6％）和女性（APC ＝－9．1％，95％CI 为－16．2％～－2．0％）人群中呈下降趋势，差异有统计学意义；而男性人群中结直肠癌死亡 ASR 的变化差异无统计学意义，APC＝－2．1％，95％CI 为－6．2％～2．0％。结论虽然结直肠癌死亡率呈现下降趋势，但是结直肠癌发病数逐年增加。因结直肠癌造成的疾病负担逐年增加，在全人群中开展结直肠癌预防控制十分必要。

Colorectal cancer temporal trend of incidence and mortality in Kunshan,Jiangsu province,2006-2013

OBJECTIVE Colorectal cancer is the major cancer for burden health,and the incidence rate showed a in creasing trend.The objective of this study was to explore the colorectal cancer incidence and death rates temporal trend inKunshan,Jiangsu province from 2006 to 2013.METHODS Colorectal cancer incidence and death cases were collectedfrom cancer registry between 2006-2013 in Kunshan city,Jiangsu province.Crude rates and age standardized rate (ASR)were calculated according to sex.Annual percent changes (APC)and 95% confidence interval (CI)were used to exami ning the time trend of incidence and mortality.RESULTS From 2006 to 2013,the colorectal cancer incidence increased infemale (APC=2.3%,95%CI:0.5%,4.2%),however,no significant changes were found in both sex (APC=0.6%,95%CI:-0.8%,1.9%)and male (APC=-0.8%,95%CI:-3.5%,1.5%).The mortality of colorectal cancer de creased significantly in both sex (APC=-5.3%,95%CI:-9.0%,-1.6%)and female (APC =-9.1%,95%CI:-16.2%,-2.0%),but stable in male according to death years (APC=-2.1%,95%CI:-6.2%,2.0%).CONCLU SION Although the mortality rate of colorectal cancer decreased significantly in Kunshan city,but the numbers colorectalcancer and the burden of diseases caused by colorectal cancer increasing year by year,it is necessary to carry out the prevention and control of colorectal cancer in the whole population.