| 喉癌组织中微血管密度与预后的关系 |
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| 引用本文： | 鲁裕玉,沈朋,丁伟. 喉癌组织中微血管密度与预后的关系[J]. 临床耳鼻咽喉头颈外科杂志, 2000, 14(12): 538-539 |
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| 作者姓名： | 鲁裕玉 沈朋 丁伟 |
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| 作者单位： | 1. 浙江大学医学院附属第一医院耳鼻咽喉科,杭州,310003
2. 浙江大学医学院附属第一医院病理科 |
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| 摘 要： | 目的 :探讨喉癌微血管密度与喉癌预后的关系。方法 :应用 F8相关抗体以 SABC法对 31例手术切除的喉癌微血管进行定量检测。结果 :微血管在喉癌组织学分级及分型中差异无显著性意义 (P >0 .0 5 ) ,而微血管在 2年后的淋巴结转移组 (10 .2 3± 0 .78)与无淋巴结转移组 (6 .38± 0 .33)中差异有显著性意义 (P <0 .0 5 )。结论 :喉癌间质内微血管生成与淋巴结转移和患者的预后有关。
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| 关 键 词： | 喉肿瘤 微血管密度 淋巴结转移 预后 |
Study on the relationship between microvascular density and prognosis in laryngeal cancer |
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| LU Yu-yu,SHEN Peng,DING Wei. Study on the relationship between microvascular density and prognosis in laryngeal cancer[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2000, 14(12): 538-539 |
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| Authors: | LU Yu-yu SHEN Peng DING Wei |
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| Affiliation: | Department of Otorhinolaryngology, First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003. |
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| Abstract: | OBJECTIVE: To study the relationship between the microvascular density(MVD) and the prognosis in laryngeal cancer. METHOD: Microvessel quantitation in 31 cases of laryngeal cancer was done with factor VIII-related antibody and SABC method. RESULT: The quantitation of microvessels in laryngeal cancer were negative of histologic grade and type, but were significantly different (P < 0.05) between metastasis (10.23 +/- 0.78) and without metastasis(6.38 +/- 0.33) two years after operation. CONCLUSION: The angiogenesis of laryngeal cancer is correlated with the lymph node metastasis and prognosis. |
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| Keywords: | Laryngeal neoplasms Microvascular density Lymphatic metastasd |
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