小剂量Isovist脑室造影CT扫描诊断脑室系统非肿瘤性疾病的实验与临床研究

用乳胶囊制成脑积水和脑室囊虫病的模型，行Ｉｓｏｖｉｓｔ造影ＣＴ扫描。结果：造影剂浓度（Ｖ／Ｖ）０．５％～１％时，ＣＴ值６５．１～１２８．３Ｈｕ，造影效果良好，浓度过小，对比度不足，效果不佳，浓度过高，将有较多伪影，可淹没或掩盖病变。以０．５％～１％Ｉｓｏｖｉｓｔ脑室造影ＣＴ扫描４４例，４３例得到明确诊断，造影效果良好，其中交通性脑积水２例，室间孔粘连１例，导水管狭窄２例，正中孔粘连５例，脑室囊虫病３３例，经手术和病理证实诊断符合率为１００％。１例注入造影剂后距扫描时间过短，造影剂尚未扩散到病变部位而失败。

EXPERIMENT AND CLINCAL STUDY OF SMALL DOSE ISOVIST CT-VENTRICULOGRAPHY FOR DIAGNOSIS OF NON-TUMOR DISEASE OF VENTRCLE SYSTEM

Model of hydrocephalus and ventricular cysticercosis were made by emulsion cyst was scaned using Isovist CT-ventriculography scanning. Result:When concentration of contrast medium was 0.5%～1%,CT volum was 65.1～128.3Hu,the effect of CT- ventricu- lography was best.As concentration was much higher,it produced false image and the focus was covered.44 patients were undergone Isovist CT- ventriculography.43 cases were definite diagnosis. Of them 2 cases with communicating hydrocephalus,1 case with foramen interven-triculare adhesion,2 cases with midbrain catheter stenosis,5 cases with median foramen of 4th ventricle adhesion,33 cases with cysticercosis. The rate of correct diagnosis was 100%.It was confirmed by operation and pathology.One patient had a fail CT- ventriculography,be-cause the interval time was short from the contrast medium emptied into lateral ventricle to CT scanning,and contrast medium had not diffused to the location of focus.