新三联疗法治疗幽门螺杆菌阳性十二指肠溃疡的对照研究

目的：探讨硫糖铝新三联疗法治疗幽门螺杆菌（ＨＰ）阳性十二指肠溃疡的疗效和安全性。方法：将ＨＰ阳性十二指肠溃疡患者随机分为３组：Ａ组（ｎ＝４５）和Ｂ组（ｎ＝４２）分别接受硫糖铝＋呋喃唑酮＋兰索拉唑和胶体铋剂＋阿莫西林＋甲硝唑治疗，Ｃ组（ｎ＝４３）接受呋喃唑酮＋兰索拉唑治疗，疗程均为２周。停药４周后复查胃镜，了解ＨＰ根除率和溃疡愈合率，并随访１年。结果：停药４周后Ａ组、Ｂ组、Ｃ组ＨＰ根除率和溃疡愈合率

A comparative study of New Triple Therapy in the Treatment of Helicobacter Pylori Positive Duodenal Ulcer

Aim:To study the efficiency and safety of new triple therapy with sucralfate in treatment of Helicobacter Pytori (HP) positive duoderal ulcer. Methods: HP Positive duodenal ulcer patients were randomly allocated into three groups: group A (n = 45)and group B(n= 42)were treated with triple therapy of sucralfate, furazlidone plus lansoprazole or colloidal bismuth subnif cate amoxicillin plus metronidazole respectively,group C (n = 43)were treated with furazolidone plus lansoprazole for 2 weeks. Then 4 weeks later all patients were examined endoscopicall. to investigate the HP eradication rate and ulcer healing rate,and fol- lowed up for I year. Results:The HP eradication rate and ulcer healing rate were 85. 3 %. 82. 2 % .61. 2 % and 86. 7 %. 83. 3 %. 65. l % in the three groups respectively,group A and group B were more satisfactory than group C(P