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骨骼肌缺血/再灌注损伤机制及防治作用的研究进展
引用本文:曹延广,徐禄基,许良,宋震坤,吴建民. 骨骼肌缺血/再灌注损伤机制及防治作用的研究进展[J]. 医学综述, 2009, 15(1): 126-129
作者姓名:曹延广  徐禄基  许良  宋震坤  吴建民
作者单位:1. 浙江中医药大学研究生学院,杭州,310053
2. 浙江省新华医院骨一科,杭州,310005
摘    要:骨骼肌缺血/再灌注损伤是骨科及显微外科临床中一种常见的严重并发症,如创伤、断肢再植术、应用止血带时间过长、筋膜间隙综合征、动脉栓塞等,都有可能造成骨骼肌缺血/再灌注损伤并带来严重的后果,甚至导致截肢或其他器官继发损伤。故对于骨骼肌的缺血/再灌注损伤机制及防止的研究目前备受重视。

关 键 词:骨骼肌  再灌注损伤  氧自由基

Progress in the Mechanism and Prevention of Skeletal Muscle Ischemia-reperfusion Injury
CAO Yan-guang,XU Lu-ji,XU Liang,SONG Zhen-kun,WU Jian-min. Progress in the Mechanism and Prevention of Skeletal Muscle Ischemia-reperfusion Injury[J]. Medical Recapitulate, 2009, 15(1): 126-129
Authors:CAO Yan-guang  XU Lu-ji  XU Liang  SONG Zhen-kun  WU Jian-min
Affiliation:CAO Yan-guang ,XU Lu-ji ,XU Liang ,SONG Zhen-kun, WU Jian-min. ( 1. Graduade School, Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China ; 2. First Orthopedic Ward ,XinHua Hospital of Zhejiang Province, Hangzhou 310005, China )
Abstract:Skeletal muscle isehemia-reperfusion (IR) is recognized in orthopaedics and mierosurgery clinic. Trauma,limb replantation, the long time of tourniquetapplication, compartment syndrome and artery embolization may cause IR, which cause serious consequences and even lend to amputation or organ damage. The researches of IR are currently focused upon.
Keywords:Skeletal muscle  Reperfusion injury  Oxygen free radicals
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