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Increasing drug resistance in extensively drug-resistant tuberculosis, South Africa
Authors:Shah N Sarita  Richardson Jessica  Moodley Prashini  Moodley Salona  Babaria Palav  Ramtahal Melissa  Heysell Scott K  Li Xuan  Moll Anthony P  Friedland Gerald  Sturm A Willem  Gandhi Neel R
Affiliation:Tugela Ferry Care and Research Collaboration, Tugela Ferry, South Africa. saritashah2@gmail.com
Abstract:We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008-April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
Keywords:Extensively drug-resistant tuberculosis   tuberculosis and other mycobacteria   HIV   drug resistance   second-line drugs   South Africa   dispatch
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