蠲痛饮对子宫内膜异位症白兔腹腔液IL-6的影响

目的:研究中药蠲痛饮对子宫内膜异位症新西兰大耳白兔腹腔液IL-6的干预作用。方法:将新西兰大耳白兔随机分成空白对照组、模型组、蠲痛饮高剂量组、中剂量组、低剂量组及达那唑组,采用白兔自体内膜子宫异位症造模方法,通过ELISA法检测各组白兔腹腔液IL-6含量,并进行统计学分析比较。结果:模型对照组腹腔液中IL-6含量较空白组有显著增高(P<0.01),蠲痛饮高剂量组、中剂量组、低剂量组能降低腹腔液中IL-6中的含量,且以高剂量组效果显著,与模型对照组比较,有统计学差异(P<0.05)。结论:蠲痛饮可能是通过降低子宫内膜异位症白兔腹腔液IL-6含量而对子宫内膜异位症产生治疗作用。

Effect of Level of IL-6 in Ascitic Fluid to White Rabbit of Juantongyin in Treating Endometriosis

Objective:Resrarch 0n intervention role of the level of IL-6 in ascitic fluid to New Zealand big-eared white rabbit of Juantongyin in treating endometriosis.Methods:Rabbits were randomly allite in 6 groups:normal groug,model groug,high Juantongyin,medium Juantongyin,low Juantongyin and Danazol group.EWT was surgically induced in the femal New Zealand rabbits first.Obsreve the effect of IL-6 of peritoneal fliud through ELISA test and the statistical analysis companison.Results:There are significantly higher in the level of IL-6 of model groug than of the nornal groug.High Juantongyin,medium Juantongyin,low Juantongyin of peritoneal fluid can reduce the content of IL-6,and in the high Juantongyin effect significantly,compared with model group,statistically significant(P<0.05).Conclusion:Juantongyin may be by lowering the level of IL-6 in ascitic fluid of white rabbit for endomtriosis produce treatment function.