脊髓灰质炎Ⅰ型重组病毒病例的流行病学研究

１９８９～１９９１年在河北省发生了脊髓灰质炎Ⅰ型自然重组株病毒的流行（为脊髓灰质炎野病毒和疫苗病毒的基因重组），对重组病毒麻痹病例进行了调查，已发现的病例分布在河北省的六个市地，占省辖市地数的５０％，病例全部为４岁以下农村儿童，发病时间以四月为高峰，８５％病例为没有接种或没有全程接种脊髓灰质炎疫苗，病例的临床症状主要是发热、腹泄、肢体麻痹，严重病例可发生呼吸困难。但有半数病例在６０天肢体麻痹恢复。

A Study on the Epidemiology of Poliomyelitis infectedwith Recombinant strain of Poliovirus Type 1

A Study on the epidemiology of poliomyelitis infected with recombinant strain of po- liovirus type 1 was reported. The recombinant poliovirus type 1 was recombinanted by wild strain and Sabin strain. Totally 1 4 cases was under 4 years old and distributed in the rural areas of 6 cities or prefectures. 85 percent of cases had not vaccinated with poliovaccine. The main symptoms were fever ,diarrhoea and paralysis , 50% of them were recovered less than 60 days.