| 切除修复交叉互补基因1、生存素与顺铂耐药的研究进展 |
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| 引用本文： | 丁静,陈余清,李伟. 切除修复交叉互补基因1、生存素与顺铂耐药的研究进展[J]. 国际呼吸杂志, 2009, 29(20). DOI: 10.3760/cma.j.issn.1673-436X.2009.020.014 |
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| 作者姓名： | 丁静 陈余清 李伟 |
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| 作者单位： | 蚌埠医学院第一附属医院呼吸内科,233000;蚌埠医学院第一附属医院呼吸内科,233000;蚌埠医学院第一附属医院呼吸内科,233000 |
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| 摘 要： | 顺铂耐药有多种复杂机制参与,大量研究表明DNA修复途径的关键基因切除修复交叉互补基因1和参与细胞凋亡和有丝分裂调控的生存素基因与顺铂耐药密切相关.
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| 关 键 词： | 切除修复交叉互补基因1 生存素 顺铂耐药 |
Research progress of excision repair cross-complementing 1,survivin and cisplatin resistance |
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| DING Jing,CHEN Yu-qing,LI Wei. Research progress of excision repair cross-complementing 1,survivin and cisplatin resistance[J]. International Journal of Respiration, 2009, 29(20). DOI: 10.3760/cma.j.issn.1673-436X.2009.020.014 |
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| Authors: | DING Jing CHEN Yu-qing LI Wei |
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| Abstract: | Cisplatin resistance is attributable to multiple intricate mechanisms.Many researches show that excision repair cross-complementing 1 which is the key gene of DNA repair pathways and survivin gene involved in apoptosis and mitosis regulation are closely related to cisplatin resistance. |
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| Keywords: | Excision repair cross-complementing 1 Survivin Cisplatin resistance |
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