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| 川贝母生物碱类成分的研究 | |
| 引用本文： | 曹新伟,张萌,李军,肖培根,陈四保,陈士林.川贝母生物碱类成分的研究[J].中草药,2009,40(1):15-17. |
| 作者姓名： | 曹新伟 张萌 李军 肖培根 陈四保 陈士林 |
| 作者单位： | 1. 中国医学科学院北京协和医学院药用植物研究所,北京,100094;深圳市中药药学及分子药理学研究重点实验室,广东,深圳518057 2. 香港科技大学生物系暨中药研发中心,香港 3. 中国医学科学院北京协和医学院药用植物研究所,北京,100094 |
| 基金项目： | 国家自然科学基金,国家科技支撑计划 |
| 摘 要： | 目的 对百合科植物川贝母Fritillaria cirrhosa的干燥鳞茎进行化学成分研究.方法 采用反复硅胶柱色谱进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构.结果 分离鉴定了8个生物碱类化合物,分别为川贝酮(chuanbeinone,Ⅰ)、梭砂贝母酮(delavinone,Ⅱ)、贝母乙素(peiminine,Ⅲ)、西贝素(imperialine,Ⅳ)、petil-idine(Ⅴ)、贝母甲素(peimine,Ⅵ)、贝母辛(peimisine,Ⅶ)、solanidine 3-O-α-L-rhamnopyranosyl-(1-2)-β-D-gluco-pyranosyl-(1-4)]-β-D-glueopyranoside(Ⅷ).结论 化合物Ⅰ、Ⅱ、Ⅳ、Ⅴ、Ⅷ为首次从本植物中分离得到. |
| 关 键 词： | 百合科 贝母属 川贝母 生物碱 |
| 收稿时间： | 2008/5/21 0:00:00 |
Alkaloid constituents of Fritillaria cirrhosa |
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| CAO Xin-wei,ZHANG Meng,LI Jun,XIAO Pei-gen,CHEN Si-bao and CHEN Shi-lin.Alkaloid constituents of Fritillaria cirrhosa[J].Chinese Traditional and Herbal Drugs,2009,40(1):15-17. | |
| Authors: | CAO Xin-wei ZHANG Meng LI Jun XIAO Pei-gen CHEN Si-bao and CHEN Shi-lin |
| Institution: | Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;State Key Laboratory of Chinese Medicine and Molecular Pharmacology,Shenzhen 518057,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;State Key Laboratory of Chinese Medicine and Molecular Pharmacology,Shenzhen 518057,China;Department of Biology and Center for Chinese Medicine,The Hong Kong University of Science and Technology,Hong Kong,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;State Key Laboratory of Chinese Medicine and Molecular Pharmacology,Shenzhen 518057,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China |
| Abstract: | |
| Keywords: | Lilliaceae Fritillaria L Fritillariacirrhosa DDon alkaloid |
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