螺旋CT联合C-反应蛋白、尿胰蛋白酶原-2检测对急性胰腺炎病情及预后的评估

探讨螺旋CT联合血清C-反应蛋白(CRP)、尿胰蛋白酶原-2(TPS-2)检测评估急性胰腺炎病情发展及预后的临床意义.回顾性分析急性胰腺炎(AP)患者79例、非胰腺炎(NAP)急腹症患者50例和健康体检者50例,分别检测血清CRP、尿TPS-2,并对19例AP组的患者血清CRP、尿TPS-2进行动态监测,同时对AP全部...

Assessment Value of Combination of Spiral CT, Serum CRP and Urine TPS-2 Test in Diagnosis and Prognosis of Acute Pancreatitis

To investigate the assessment efficiency of the severity and prognosis of acute pancreatitis by the combination of spiral CT,serum CRP and urine TPS-2 test,79 cases of acute pancreatitis（AP）,50 cases of acute abdomen patients with non acute pancreatitis（NAP） and 50 cases of healthy persons with physical examination were retrospectively analyzed.The serum CRP and urine TPS-2 were detected,and serum CRP and urine TPS-2 of 19 cases in Group AP were dynamic monitored.The spiral CT scanning was performed at the same time,and then the data and CT findings were comprehensive analyzed.According to Balthazar CT grade： the patients were graded as Grade A（16 cases）,Grade B（19 cases）,Grade C（23 cases）,Grade D（15 cases） and Grade E（6 cases）.Grade A-C were for mild pancreatitis（MAP）,and Grade D-E were for severe pancreatitis（SAP）.The serum CRP level of Group SAP was significantly higher than that in Group MAP（P〈0.05）.The positive rate of urine TPS-2 in Group AP was higher than that in Group NAP（P〈0.05）.The positive rate of urine TPS-2 in Group SAP was higher than that of Group MAP,but the difference did not have statistical significance.The serum CPR concentration of Grade C-E was significantly higher than that of Grade A-B.The positive rate of urine TPS-2 of Grade B-E was significantly higher than that of Grade A,but the difference did not have statistical significance,and it had no statistical significance of positive rate of urine TPS-2 between Grade B-E.The combination of spiral CT,serum CRP and urine TPS-2 test has important clinical meaning in the evaluation,monitoring and prognosis of acute pancreatitis.