| 慢性肾脏病患者肾小球滤过率与血清Cystatin C相关性分析 |
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| 引用本文： | 杨斌. 慢性肾脏病患者肾小球滤过率与血清Cystatin C相关性分析[J]. 标记免疫分析与临床, 2011, 18(5): 300-303 |
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| 作者姓名： | 杨斌 |
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| 作者单位： | 湖北省谷城县人民医院检验科,湖北,谷城,441700 |
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| 摘 要： | 探讨慢性肾脏病(chronic kidney disease,CKD)患者肾小球滤过率(glomentlar filtration rate,GFR)与血清半胱氨酸蛋白酶抑制剂C(cystatin C)的相关性.采用颗粒增强免疫浊度分析法测定340例CKD组患者和60名对照组血清cystatin C,全自动生化分析仪检...
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| 关 键 词： | 血清半胱氨酸蛋白酶抑制剂 慢性肾脏病 肾小球滤过率 血清肌酐 颗粒增强免疫浊度分析法 相关性分析 |
Correlation Analysis Between Glomerular Filtration Rate and Serum Cystatin C in Patients with Chronic Kidney Disease |
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| YANG Bin. Correlation Analysis Between Glomerular Filtration Rate and Serum Cystatin C in Patients with Chronic Kidney Disease[J]. Labeled Immunoassays and Clinical Medicine, 2011, 18(5): 300-303 |
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| Authors: | YANG Bin |
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| Affiliation: | YANG Bin(Department of Clinical Laboratory,Gucheng People＇s Hospital,Gucheng 441700,China) |
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| Abstract: | To explore the correlation between glomerular filtration rate（GFR） and serum cystatin C in patients with chronic kidney disease（CKD）.The serum cystatin C levels in 340 patients with CKD and 60 health controls were determined by particles enhance turbidimetric immune analysis.The GFR was calculated by the simplified equation derived from the modification of diet in renal disease study（MDRD）.The results showed that the GFR was significant negatively correlated with cystatin C and SCr（P0.01） and cystatin C had a stronger correlations with GFR.There was significant statistical difference between cystatin C and SCr（P0.05）.The reflect glomerular filtration function of cystatin C was more accurately than that SCr,it may be useful for the early diagnosis of GFR function in the patients with chronic kidney disease. |
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| Keywords: | Cystatin C Chronic kidney disease Clomerular filtration rate SCr Particles enhance turbidimetric immune analysis Correlation |
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