较早发病的精神分裂症临床特点及预后研究

目的:探讨青春期与成年早期发生的精神分裂症临床特征、治疗预后,并进行对照研究。方法:以首次精神病性症状出现于25岁前随访治疗1年的精神分裂症患者,按首发年龄18岁以下或18岁及以上分为青春期组和成年早期组加以临床对照。结果:两组早期发育风险因素和精神病早期症状中差异无显著性,精神症状全面量表(CPRS)评定中,首发时青春期组更多反映出为小事烦恼担忧、做事犹豫不决和其他幻觉,成年早期组以被控制感、思维紊乱、被害观念、妄想性心境、其他幻听等较为多见(P<0.05或P<0.01)。结论:早发和成年早期发生的精神分裂症,都有较多症状残留。

Clinical characteristics of earlier onset schizophrenia

Objective: To explore the clinical characteristics and prognoses after treatment in patients with schizophrenia who had first episode in adolescence or earlier adult and conducted a comparison study. Method:Patients with schizophrenia,who had first episode before the age of 25 and then were followed-up for one year,were divided into adolescence group and earlier adult group according to the first episode age less or more than 18 years. Results:There were no significant differences between the two groups in ...