| 促红细胞生成素的细胞生物学特性与缺血性脑损伤 |
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| 引用本文： | ZHU Bo,叶铁虎.促红细胞生成素的细胞生物学特性与缺血性脑损伤[J].国际麻醉学与复苏杂志,2008,29(4). |
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| 作者姓名： | ZHU Bo 叶铁虎 |
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| 作者单位： | 1. Department of Anesthesiology,the Pekung Union Medical College Hospital, Pekiny Unin Medical College, Beijing 100730, China
2. 中国协和医科大学,北京协和医院麻醉科,中国医学科学院,100730 |
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| 摘 要： | 促红细胞生成素(EPO)在调节红细胞生成中发挥重要作用,长期以来广泛用于肾性贫血的治疗.近年来研究证实EPO亦具有神经营养、神经保护和调节胚胎发育的作用,其机制可能与直接抑制神经元凋亡和间接促进血管生长及新生血管的形成有关.
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| 关 键 词： | 促红细胞生成素 缺血性脑损伤 |
The cellular biology of erythropoietin and its effects on cerebral ischemia |
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| ZHU Bo,YE Tie-hu.The cellular biology of erythropoietin and its effects on cerebral ischemia[J].international journal of anesthesiology and resuscitation,2008,29(4). |
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| Authors: | ZHU Bo YE Tie-hu |
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| Abstract: | Erythropoietin(EPO) plays a crucial role in the regulation of hematopoiesis and has been used extensively in the management of uremic anemia. Recent studies have brought to light a positive effect of EPO in neuronal nutrition, neuroprotection and regulating embryo development. The patho-physiological mechanism of EPO may be related to directly protecting neuronal cell from apoptosis and indirectly facilitating angiogenesis and neovascularization. |
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| Keywords: | erythropoietin cerebral ischemia |
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