胸腔内注入尿激酶对结核性胸膜炎的疗效观察

目的探讨尿激酶胸腔内注射治疗结核性胸膜炎的效果。方法将82例结核性胸膜炎患者随机分为治疗组和对照组。治疗组在胸穿抽液后注射生理盐水20ml稀释尿激酶10万u,对照组在抽液后注入生理盐水20ml,两组抗结核化疗方案相同。结果治疗组总有效率97.6%,优于对照组82.9%(P<0.05);抽液量2486ml,优于对照组1817ml(P<0.05),治疗组胸膜增厚粘连发生率明显减少(P<0.05)。结论尿激酶对结核性渗出性胸膜炎有辅助治疗作用,可减少胸膜粘连。

Effect of interpleural injection with ultrasound-guided drainage in treatment for tuberculous effusion

Objective To investigate the effects and side effects of pleural space injection with ultrasound-guided drainage in treatment of tuberculous pleural effusion.Methods 82 cases with tuberculous pleural effusion were randomly divided into two groups:treatment group and control group.Same types of chemotherapeutic regimen and withdrawing effusion were taken in both groups.100000lU urokinase(diluted by 20ml normal saline)was injected into pleural space only in the treatment group.Results The total effective rates were 97.6% in treatment group and 82.9% in the control group:The aspiration volume was 2486 ml in the treatment group and 1817 ml in the control group;the incidence rate of pleural thickening was apparently decreasing.Conclusion It is effective in using ultrasound-guided drainage in the treatment of tuberculous pleurisy patients.The incidence rate of pleural thickening was apparently decreasing.