Primary progressive aphasia: a case report |
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| Authors: | Tamas Gergely Nagy Ilona Jelencsik Imre Szirmai |
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| Affiliation: | Department of Neurology, Semmelweis Medical University, Budapest, Hungary. |
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| Abstract: | We report a 69-year-old male patient whose motor aphasia started at the age of 61. The language disability remained isolated and progressed over a period of eight years without any additional cognitive deficits. Computed tomography (CT) and magnetic resonance imaging (MRI) showed moderate cortical atrophy with frontal dominance. Single photon emission tomography (SPECT) showed hypoperfusion in the frontotemporoparietal region, positron emission tomography (PET) demonstrated a global cortical reduction of glucose utilization with a lesser decrement in the occipital lobes. The clinical symptoms and the neuropsychological findings fit the diagnosis of primary progressive aphasia. |
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| Keywords: | primary progressive aphasia focal cortical degeneration syndrome dementia regional cerebral blood flow and metabolism |
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