脂肪肝病人血液流变学的临床观察

目的对临床确诊的脂肪肝病人,同时伴有甘油三酯增高者,比较其血液流变学各参数的变化,以探讨对临床脂肪肝诊断的实用价值.方法分别测定86例患者的全血粘度、血浆粘度、甘油三酯等9项血液流变学指标.结果 86例脂肪肝病人全血粘度(高切、低切)、红细胞电泳时间及甘油三酯同时增高者61例,占70.9%.全血粘度(高切、中切、低切)、血浆粘度、全血还原粘度、红细胞聚集指数、红细胞电泳时间、甘油三酯同时增高者19例,占22.1%.单纯全血粘度低切增高者6例,占7%.结论脂肪肝病人血液流变学各参数的影响主要是全血粘度及红细胞电泳时间有明显的改变,甘油三酯的增高对血浆粘度及全血还原粘度影响不太明显.可作为临床对脂肪肝病人辅助诊断检查的一项重要参考指标.

Clinical Observation Fatty Liver Patient Hemorheology

Objective To compare the hemorheology parameter of 86 clinical cases with triglyceride increase,who were diagnosed fatty liver in order to observe the practical value of fatty liver diagnosis.Methods 1) Taking 3ml venous blood from an empty stomach,and mixing it into heparin test tube,to measure blood viscosity and then separate serum and measure serum viscosity.2) Taking 2ml blood from patient's elbow vein to separate serum test triglyceride.Results 61 patients(70.9%) demonstrated high shear,low shear blood viscosity and RBC electrophoresis time simultaneous increase.19 patients(22.1%) showed high shear,medium shear,low shear,plasma viscosity,reduced viscosity,erythrocyte aggregation index,RBC electrophoresis time,triglyceride increase simultaneously.6 patients showed low shear whole blood viscocity increase purely.Conclusion Major change of hemorheology parameters of fatty live patients has obvious change of whole bood viscocity and RBC electrophoresis time,increased triglyceride does not affect whole blood viscocity and plasma viscocity obviously,which can be used as auxiliary index for clinical fatty liver patients diagnosis.