老年非瓣膜性心房颤动住院患者衰弱现状及影响因素分析

目的 调查老年非瓣膜性心房颤动住院患者的衰弱现状及其影响因素。 方法 采用便利抽样法,选取2020年3月—10月在温州市某三级甲等医院心血管内科住院的183例老年非瓣膜性心房颤动患者,采用一般资料调查表、FRAIL衰弱问卷、Barthel指数评定量表、Padua风险评估表进行调查。采用Logistic回归分析老年非瓣膜性心房颤动住院患者衰弱的影响因素。 结果 老年非瓣膜性心房颤动住院患者衰弱前期和衰弱的发生率分别为39.9%和28.4%,仅有31.7%患者无衰弱。Logistic回归结果显示,年龄、性别、左心室射血分数、左心房内径、Barthel指数得分和Padua得分是老年非瓣膜性心房颤动患者衰弱的影响因素（P<0.05）。 结论 老年非瓣膜性心房颤动患者合并衰弱的发生率高。高龄、左心室射血分数低、左心房内径增大等非瓣膜性心房颤动患者更易出现衰弱。

The current status and influencing factors analysis of frailty in the elderly hospitalized patients with non-valvular atrial fibrillation

Objective To investigate the current status of frailty in elderly hospitalized patients with non-valvular atrial fibrillation（NVAF） and to analyze the influencing factors. Methods The convenience sampling method was used to select 183 elderly patients aged 60 years and older who were diagnosed with NVAF and hospitalized in the Department of Cardiovascular Medicine of a tertiary hospital in Wenzhou from March 2020 to October 2020.The general patient data,laboratory parameters,cardiac ultrasound parameters,and health data were collected by the General Information Questionnaire,Frail Frailty Questionnaire,Barthel Index,Activity of Daily Living Scale（ADL）and Padua score for risks of deep vein thrombosis in medical inpatients. Statistical methods including single factor and multifactor analysis were conducted for influencing factors of frailty in the elderly patients with atrial fibrillation. Results The pre-frailty and frailty rates in 183 elderly patients with NVAF were 39.9% and 28.4%,respectively,and only 31.7% were non-frailty. The results of ordered multiple Logistic regression showed that age,sex,cardiac ejection fraction,left atrial internal diameter,and ADL were influential factors in the frailty of elderly patients with NVAF（P<0.05）. Conclusion Elderly patients with NVAF have a high incidence of frailty and a large proportion of patients are in the pre-frailty. Age,sex,cardiac ejection fraction,left atrial internal diameter,ADL and the deep vein thrombosis risk are influential factors in frailty. Frailty screening and management should be carried out as early as possible during hospitalization for elderly patients with NVAF to improve their ADL and quality of life.