超声造影对经导管肝动脉栓塞化疗术治疗肝细胞癌患者效果的评价

目的 探讨采用经肝动脉超声造影评价经导管肝动脉栓塞化疗(TACE)术后即刻栓塞效果,并预测肿瘤短期疗效.方法 选取2018年9月至2019年3月在解放军总医院第一医学中心因肝肿瘤行TACE治疗的肝细胞癌患者39例,共50个肝细胞癌病灶术前及术后即刻行经肝动脉超声造影,依据术后与术前肿瘤内部增强最大面积占比及术后与术前引...

Contrast-enhanced ultrasound for evaluation of efficacy of transcatheter hepatic artery embolization in patients with hepatocellular carcinoma

ObjectiveTo investigate the feasibility of evaluating the effect of embolization by transhepatic arterial contrast-enhanced ultrasonography immediately after transarterial chemoembolization (TACE) to predict the short-term curative effect for hepatocellular carcinoma (HCC). MethodsA total of 50 HCC lesions in 39 patients treated by TACE underwent transhepatic artery contrast-enhanced ultrasonography before and immediately after operation at the First Medical Center of Chinese PLA General Hospital from September 2018 to March 2019. According to the maximum area ratio of internal enhancement of the tumor after surgery and before surgery and the maximum covering ratio of drainage area before and after surgery, Spearman correlation analysis was used to compare MRI results within 1 to 3 months after TACE between groups. ResultsThe effect of embolization evaluated by immediate postoperative tumor enhancement ratio and postoperative covering ratio of drainage area was related to the short-term curative effect judged by modified response evalution criteria in solid tumors (mRECIST), and the postoperative covering ratio of drainage area had a more significant correlation (r=0.516, P＜0.001 and r=0.716, P＜0.001, respectively). ConclusionThe evaluation of embolization effect immediately after TACE by transhepatic artery contrast-enhanced ultrasonography has a high correlation with the short-term curative effect evaluated by mRECIST, which can provide a good imaging reference value for predicting the short-term curative effect after tumor operation.