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基于深度学习的超声影像诊断对终末期慢性肾病的价值
引用本文:李广涵,刘健,马立勇,董梦超,武敬平,张波,李文歌,郑敏. 基于深度学习的超声影像诊断对终末期慢性肾病的价值[J]. 中华医学超声杂志(电子版), 2021, 18(6): 611-615. DOI: 10.3877/cma.j.issn.1672-6448.2021.06.012
作者姓名:李广涵  刘健  马立勇  董梦超  武敬平  张波  李文歌  郑敏
作者单位:1. 100029 北京,中日友好医院超声医学科2. 100029 北京,中日友好医院肾病科3. 264209 哈尔滨工业大学(威海)信息科学与工程学院
基金项目:国家重点研发计划政府间国际科技创新合作重点专项(2017YFE0110500); 山东省自然科学基金项目(ZR2018MF026); 山东省重点研发计划(2019GGX101054)
摘    要:目的 探讨基于深度学习的卷积神经网络模型DenseNet121对终末期肾病的诊断价值.方法 回顾性选择2019年1月1日至9月30日期间中日友好医院诊断为终末期肾病的489张肾超声影像和对照组450张健康肾超声影像.采用深度卷积神经网络模型DenseNet121进行网络的训练和验证,把是否为终末期肾病作为参考标准.然后...

关 键 词:慢性肾病  超声  深度学习  诊断
收稿时间:2021-03-15

Deep learning-based model for ultrasound diagnosis of end-stage chronic kidney disease
Guanghan Li,Jian Liu,Liyong Ma,Mengchao Dong,Jingping Wu,Bo Zhang,Wenge Li,Min Zheng. Deep learning-based model for ultrasound diagnosis of end-stage chronic kidney disease[J]. Chinese Journal of Medical Ultrasound, 2021, 18(6): 611-615. DOI: 10.3877/cma.j.issn.1672-6448.2021.06.012
Authors:Guanghan Li  Jian Liu  Liyong Ma  Mengchao Dong  Jingping Wu  Bo Zhang  Wenge Li  Min Zheng
Affiliation:1. Department of Ultrasound Medicine, China-Japan Friendship Hospital, Beijing 100029, China2. School of Information Science and Engineering, Harbin Institute of Technology, Weihai 264209, China3. Department of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China
Abstract:ObjectiveTo evaluate the diagnostic value of the convolution neural network model DenseNet121 based on deep learning in the diagnosis of end-stage renal disease (ESRD). MethodsIn this retrospective study, 489 kidney ultrasound images of patients diagnosed with end-stage renal disease from January 1, 2019 to September 30, 2019 and 450 kidney ultrasound images of healthy controls were selected at China-Japan Friendship Hospital. The deep learning-based supervised convolutional neural network model DenseNet121 was used for network training and verification. According to whether it was end-stage renal disease or not, the prediction results of the deep learning-based model were compared with the prediction results of professional imaging physicians. Receiver operating characteristic (ROC) curve analysis was used to evaluate the performance of the deep learning-based model, the accuracy, specificity, sensitivity, and area under the curve (AUC) were used as metrics to compare the performance of the deep learning-based model and professional imaging physicians, and Delong was used to compare the difference of AUC. ResultsThe prediction accuracy of professional imaging physicians for end-stage renal disease was 89.36%, the sensitivity was 81.63%, the specificity was 97.77%, and the AUC was 0.897. The prediction accuracy of the deep learning-based convolution neural network model DenseNet121 for end-stage renal disease was 93.51%, the sensitivity was 96.12%, the specificity was 90.66%, and the AUC was 0.934. Compared with professional physicians, the DenseNet121 model had higher diagnostic ability (Z=3.034, P=0.002). ConclusionThe ultrasonic diagnosis method based on deep learning shows high diagnostic performance, and it has the potential to assist professional imaging physicians in the diagnosis of end-stage renal disease.
Keywords:Chronic kidney disease  Ultrasound  Deep learning  Diagnosis  
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