| IL-17/IL-17R与恶性肿瘤 |
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| 引用本文： | 陈曦,朱波,陈正堂.IL-17/IL-17R与恶性肿瘤[J].免疫学杂志,2010(4). |
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| 作者姓名： | 陈曦 朱波 陈正堂 |
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| 作者单位： | 第三军医大学新桥医院全军肿瘤中心; |
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| 基金项目： | 国家自然科学基金资助项目(30870516);;全国博士学位论文作者专项资金资助项目(200776) |
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| 摘 要： | IL-17是新近被确认的一种细胞因子,由T细胞、中性粒细胞等产生,其靶细胞分布广泛。IL-17具有强大的招募中性粒细胞、促进多种细胞释放炎性因子、促进细胞增殖的作用,被认为参与了机体多种炎症疾病、自身免疫性疾病和肿瘤等的发生,本文就IL-17/IL-17R在肿瘤中的研究进展做一综述。
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| 关 键 词： | IL-17 IL-17R 肿瘤 |
IL-17/IL-17R and cancer |
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| CHEN Xi,ZHU Bo,CHEN Zhengtang Institute of Cancer,Xinqiao Hospital,Third Military Medical University,Chongqing ,China.IL-17/IL-17R and cancer[J].Immunological Journal,2010(4). |
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| Authors: | CHEN Xi ZHU Bo CHEN Zhengtang Institute of Cancer Xinqiao Hospital Third Military Medical University Chongqing China |
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| Institution: | CHEN Xi,ZHU Bo,CHEN Zhengtang Institute of Cancer,Xinqiao Hospital,Third Military Medical University,Chongqing 400037,China |
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| Abstract: | Interleukin-17(IL-17) is a newly identified pro-inflammatory cytokine secreted by CD4~+ T cells and neutrophils.IL-17, which has many functions and target cells,has been shown to enhance the recruitment of neutrophils,the expression of pro-inflammatory factor,and the proliferation of cells.IL-17 has been considered to be involved in the development of inflammation,self-immunity disease, and cancer.In this article,we summarized the potential role of IL-17 in cancer. |
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| Keywords: | IL-17 IL-17R Cancer |
| 本文献已被 CNKI 等数据库收录！ |
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