肺炎并全身炎症反应综合征患儿血糖和C反应蛋白的变化

目的　探讨血糖、C反应蛋白 (CRP)在肺炎并全身炎症反应综合征 (SIRS)患儿中的改变及其意义。方法　选择 6 2例肺炎并SIRS患儿 ,动态测定血糖及CRP ,同时选择非SIRS的肺炎患儿和正常儿童作对照。结果　非SIRS组血糖与正常对照组比较差异无显著意义 (P >0 0 5 ) ,而CRP显著高于正常对照组 (P<0 0 1) ;SIRS组血糖和CRP均显著高于非SIRS组 (P <0 0 1) ;具有SIRS诊断标准 3项以上的患儿 4 8h血糖和第 5dCRP持续不降 ,发生多器官功能不全综合征 (MODS)率明显增高 (P <0 0 1)。结论　肺炎时血糖和CRP联合检测有助于准确评估病情的危重度 ,血糖和CRP持续性升高 ,预示着MODS的可能发生。

The changes in blood sugar and CRP in infantile pneumonia associated with SIRS

Objective To assess the changes and significance of blood sugar,C-reactive protein(CRP) in children with infantile pneumonia associated with systemic inflammatory response syndrome(SIRS).Methods Levels of blood sugar and CRP were measured in 62 children with pneumonia associated with SIRS(group A),and compared with those in children with pneumonia of non-SIRS(group B) and normal children(control group).Results There was insignificant difference in blood sugar between group B and control group(P>0.05),but CRP was siginificantly higher in group B than control group(P<0.01).The levels of blood sugar and CRP in group A were all significantly higher than those in group B(P<0.01).Sick children with three items of standard diagnostic indexes for SIRS kept high levels of 48-hour blood sugar and the fifth-day CRP(P<0.01),so the incidence of multiple organ dysfunction syndrome(MODS) increased significantly(P<0.01).Conclusion The combined detection of blood sugar and CRP might help in accurately assessing the severity degree of SIRS.The continuously elevated blood sugar and CRP might forcast the possibility of MODS.