代谢组学技术在针刺研究设计中的质量控制

代谢组学技术作为系统生物学的重要组成部分已被广泛地应用于多个领域,但其结果易受多种因素的影响。近来本课题组率先将代谢组学这一新兴技术引入针刺临床研究领域,并针对人体代谢物易受外界刺激干扰的特点,参照文献设计了该技术在针刺研究中的质量控制方法,包括严格筛选受试对象,适当控制受试对象的饮食、运动、昼夜节律,规范样本的采集、处理和保存以及统一针刺刺激量等措施,以便减少干扰,突出针刺作用。该方法有助于提高代谢组学技术应用于针刺领域的研究质量。

Quality Control of Metabonomics in Acupuncture Research Design

As a part of systems biology,metabonomics has been widely used in many areas.Recently,our research group has taken the lead to introduce metabonomics,an promising technology,into the field of clinical acupuncture research.Because the outcome of metabonomics would be influenced by variety factors such as spicy food and heavy exercise as literature reported,we took some measures to control the quality of the whole study and thus to emphasize acupuncture effects.These methods include restrictions of subject's ...