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Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis
Authors:Gupta Amita  Chandrasekhar Aditya  Gupte Nikhil  Patil Sandesh  Bhosale Ramesh  Sambarey Pradeep  Ghorpade Shivahari  Nayak Uma  Garda Laila  Sastry Jayagowri  Bharadwaj Renu  Bollinger Robert C;Byramjee Jeejeebhoy Medical College–Johns Hopkins University Study Group
Institution:Dept of Medicine, Division of Infectious Diseases,Centre for Clinical Global Health Education, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA. agupta25@jhmi.edu
Abstract:We evaluated tuberculosis (TB) screening among 799 human immunodeficiency virus (HIV)-infected pregnant women in India. Eleven (1.4%) had active TB. The negative predictive value of screening using cough, fever, night sweats, or weight loss was 99.3%. Tuberculin skin test and targeted chest radiography provided no substantial benefit. TB symptom screening, as recommended by the World Health Organization, is effective for ruling out TB in HIV-infected pregnant women.
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