| 养血清脑颗粒对偏头痛患者LPA、TNF水平影响的研究 |
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| 引用本文： | 齐进兴,赵亮,朱华伟,孙建奎,赵彦玲,范肿鹏.养血清脑颗粒对偏头痛患者LPA、TNF水平影响的研究[J].中国实用神经疾病杂志,2009,12(1). |
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| 作者姓名： | 齐进兴 赵亮 朱华伟 孙建奎 赵彦玲 范肿鹏 |
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| 作者单位： | 河南安阳地区医院神经内科,安阳,455000 |
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| 摘 要： | 目的 探讨养血清脑颗粒对偏头痛患者溶血磷脂酸(LPA)、肿瘤坏死因子(TNF)水平的影响.方法 治疗组:160例,采用盐酸氟桂利嗪胶囊加养血清脑颗粒治疗;对照组:58例,单独使用盐酸氟桂利嗪胶囊;健康组:35例.均采用酶免法及严格按试剂说明书操作,对3组受检者外周血LPA、TNF水平进行了检测.结果 治疗组偏头痛患者外周血LPA及TNF水平在用药24h前和用药2周均较健康组高(P＜0.01),用药4周基本恢复健康组水平(P＞0.05);治疗组在用药2周、4周LPA、TNF水平均较对照组低(P＜0.05).而对照组在用药的2周、4周均较健康组高(P＜0.01),P＜0.05).结论 采用盐酸氟桂利嗪胶囊加养血清脑颗粒较单独使用盐酸氟桂利嗪胶囊治疗能更显著的降低偏头痛患者外周血LPA及TNF水平,并能更快更好的缓解头痛症状.提示LPA、TNF增高在偏头痛发作期的发病中发挥一定作用,养血清脑颗粒可有效降低偏头痛发作时LPA、TNF水平和缓解头痛症状.
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| 关 键 词： | 偏头痛 养血清脑颗粒 |
The effect of Yangxueqingnao Granula on LPA and TNF level in patients with migraine |
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| Qi Jinxing,Zhao Liang,Zhu Huawei,et al..The effect of Yangxueqingnao Granula on LPA and TNF level in patients with migraine[J].Chinese Journal of Practical Neruous Diseases,2009,12(1). |
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| Authors: | Qi Jinxing Zhao Liang Zhu Huawei |
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| Institution: | Qi Jinxing,Zhao Liang,Zhu Huawei,et al.Department of Neurology,the Anyang Area Hospital,Anyang 455000,Henan,China |
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| Abstract: | Objective To explore the effect of Yangxueqingnao Granula on LPA and TNF level in patients with migraine.Methods Study group(160 cases) were given flunarizine hydrochloride capsules and Yangxueqingnao Granula.Control group(58 cases) were given only flunarizine hydrochloride capsules.35 cases of healthy people composed health group.The serum level of LPA and TNF of three group was detected by enzyme-immunoassay method which was implemented strictly according to specification.Results The serum level of LPA an... |
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| Keywords: | LPA TNF |
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