舒芬太尼术后静脉镇痛在开胸手术的临床观察

目的：探讨用舒芬太尼在开胸手术术后静脉镇痛的可行性和安全性。方法：80例ASAⅠ～Ⅱ级择期开胸手术病人，随机分为M组和S组，每组40例。术后行自控静脉镇痛，镇痛药物分别为吗啡40mg、舒芬太尼100ug；分别配加托烷司琼10mg并以生理盐水稀释至100ml。记录行自控镇痛后4、8、16、24h的用药量；PCA按压次数；镇痛VAS评分、不良反应及生命体征情况。结果：两组均可获得有效的镇痛效果。VAS评分S组显著低于M组。PCA按压次数F组比M组少；24h的用药量两组无显著性差异；M组副反应较多，恶心发生率高。结论：舒芬太尼用于开胸术后静脉镇痛安全有效，而且副反应较少。

Clinical Study of Intravenous Analgesia with Sufentanil After Thoracotomy

Objective： To evaluate the clinical efficacy and safety of intravenous analgesia with sufentanil after thoracotomy. Method ： 80 patients with ASA Ⅰ～Ⅱwere randomly divided into M group（ with morphine 0.4mg/ml） and S group（with sufentanil 1 ug/ml） , 40 eases in each group. The drug doses at 4, 8,16,24 hour, pressing times of PCA, the visual analogue score （VAS）, the side -effects and life vital signs were recorded. Result： Both of two groups had effective analgesia. The VAS was significantly lower in S group than that in M group. The pressing times of PCA were significantly lower in M group than those in S group. The doses of drug using were no significantly difference. The side effects like nausea occurred more in M group than that in S group. Conclusion： It is an effective way to intravenous analgesia with sufentanil after thoracotomy, and with less side effects.