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| 姜黄素联合维生素E预防大鼠肝纤维化的形态学研究 | |
| 引用本文： | 赵莹莹,魏亭,江帆,杨宁,唐杭燕,陈辉,钟秀宏. 姜黄素联合维生素E预防大鼠肝纤维化的形态学研究[J]. 吉林医药学院学报, 2011, 32(4): 189-191 |
| 作者姓名： | 赵莹莹 魏亭 江帆 杨宁 唐杭燕 陈辉 钟秀宏 |
| 作者单位： | 1. 吉林医药学院 2007级英语护理本科班 吉林 吉林132013 2. 吉林医药学院 2006级英语护理本科班 吉林 吉林132013 3. 吉林医药学院 2008级临床医学本科班 吉林 吉林132013 4. 吉林医药学院 病理学教研室 吉林 吉林132013 |
| 基金项目： | 吉林医药学院大学生科研基金资助项目(吉医学科字[2009]第11号) |
| 摘 要： | 目的观察研究姜黄素（Cur）和维生素E（VE）联用预防大鼠肝纤维化的疗效。方法建立四氯化碳（CCl4）大鼠肝纤维化模型,Cur和VE及两药联用预防后观察肝左叶HE染色和Masson染色下形态学变化。结果 HE染色与Masson染色结果与模型组比较,预防组较模型组肝纤维化有明显改善,以药物联用组尤为显著。结论 Cur和VE对CCl4诱导的肝纤维化均有预防作用,两者合用预防肝纤维化效果更佳,具有协同作用。 |
| 关 键 词： | 肝纤维化 CCl4 姜黄素 维生素E |
Effect of curcumin and vitamin E combination therapy on liver pathomorphology of the liver fibrosis in rats |
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| ZHAO Ying-ying,WEI Ting,JIANG Fan,YANG Ning,TANG Hang-yan,CHEN Hui,ZHONG Xiu-hong. Effect of curcumin and vitamin E combination therapy on liver pathomorphology of the liver fibrosis in rats[J]. Journal of Jilin Medical College, 2011, 32(4): 189-191 | |
| Authors: | ZHAO Ying-ying WEI Ting JIANG Fan YANG Ning TANG Hang-yan CHEN Hui ZHONG Xiu-hong |
| Affiliation: | ZHAO Ying-ying1,WEI Ting2,JIANG Fan1,YANG Ning1,TANG Hang-yan1,CHEN Hui3,ZHONG Xiu-hong4(Jilin Medical College:1.2007 Students from Department of Nursing,2.2006 Students from Department of Nursing,3.2008 Students from Department of Clinical Medicine,4.Department of Pathology,Jilin City,Jilin Province,132013,China) |
| Abstract: | Objective To observe the preventive effect of combination of curcumin and vitamin E on liver fibrosis in rats.Methods The liver fibrosis model was induced by hypodermic injection of carbon tetrachloride(CCl4) in rats.The morphological structure in hepatic left lobule were observed through HE staining and Masson trichrome staining.Results The observation on staining showed that the liver fibrosis improved in drug group,especially those in drug combination group when compared with the model group.Conclusion B... |
| Keywords: | liver fibrosis CCl4 curcumin VE |
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