| 响应曲面法提取苦白蹄中总三萜成分 |
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| 引用本文： | 刘健,郭淑英. 响应曲面法提取苦白蹄中总三萜成分[J]. 吉林医药学院学报, 2011, 32(5): 278-282 |
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| 作者姓名： | 刘健 郭淑英 |
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| 作者单位： | 吉林医药学院药物分析教研室,吉林 吉林,132013 |
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| 基金项目： | 吉林省教育厅项目(20090506) |
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| 摘 要： | 目的采用响应对苦白蹄中总三萜类成分进行提取。方法在单因素试验基础上,利用响应曲面法中心组合设计,采用超声波辅助萃取法对苦白蹄中总三萜提取工艺参数进行优化分析。选择超声频率、超声时间和超声温度作为优化因素,研究不同因素水平对苦白蹄总三萜得率的影响。结果通过响应面分析得到总三萜提取的最优条件：超声频率70 Hz、提取时间35 min、提取温度40℃。结论总三萜类化合物提取的实测结果与响应曲面拟合所得方程的预测值符合良好。
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| 关 键 词： | 苦白蹄 总三萜 响应曲面法 超声辅助提取 |
Extracting total triterpenes from Fomes officinalis ames with response surface methodology |
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| LIU Jian,GUO Shu-ying. Extracting total triterpenes from Fomes officinalis ames with response surface methodology[J]. Journal of Jilin Medical College, 2011, 32(5): 278-282 |
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| Authors: | LIU Jian GUO Shu-ying |
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| Affiliation: | LIU Jian,GUO Shu-ying(Department of Pharmmaceutical Analysis,Jilin Medical College,Jilin City,Jilin Province,132013,China) |
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| Abstract: | Objective Total triterpenes were extracted from Fomes officinalis ames with response surface method.Methods The ultrasonic-assisted extraction process of total triterpenoids from Fomes officinalis ames was studied.Based on the experiment of single factor,the mathematical regression model was established about the dependent variable(extraction yield of triterpenes) and independent variables(Ultrasonic frequency,extraction time,extraction temperature) through Box-Benhnken center composite design and response ... |
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| Keywords: | Fomes officinalis ames total triterpenoids response surface methodology ultrasonic-assisted extraction |
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