| 高速逆流色谱技术在药物研究开发中的应用 |
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| 引用本文： | 曹学丽.高速逆流色谱技术在药物研究开发中的应用[J].世界科学技术,2007,9(1):54-58. |
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| 作者姓名： | 曹学丽 |
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| 作者单位： | 北京工商大学化学与环境工程学院/北京市植物资源研究开发重点实验室 北京100037 |
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| 基金项目： | 北京市教育委员会科技发展教育计划项目;北京市自然科学基金 |
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| 摘 要： | 对高速逆流色谱(HSCCC)技术。在天然药用植物活性成分分离及标准品制备、中药指纹图谱分析、天然新药的研发和活性部位筛选等方面中的应用及其在生物药物以及药物工业化领域的应用发展趋势进行了综述。
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| 关 键 词： | 高速逆流色谱 药物研究开发 活性成分分离 |
| 收稿时间： | 2006-10-10 |
| 修稿时间： | 2006-11-30 |
HSCCC and Its Applications in Medical Research |
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| Cao Xueli.HSCCC and Its Applications in Medical Research[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2007,9(1):54-58. |
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| Authors: | Cao Xueli |
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| Institution: | Beijing Key Laboratory of Plant Resource Research and Development, Beijing Technology and Business University, Beijing 100037 |
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| Abstract: | High-speed countercurrent chromatography, or HSCCC, is a continuous liquid-liquid partition chromatography developed in the 1980s. In recent years, HSCCC has been widely used in research and development of traditional Chinese medicine, biomedicine, natural products, functional foods and cosmetics, including separating natural active components from plant resources, developing standard reference material of natural components, fingerprint analysis of traditional Chinese medicine, and selecting and screening new natural medicines. A review is presented in this paper, on HSCCC separation mechanism, instrumentation, operation, and its applications in TCM research. |
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| Keywords: | High-speed countercurrent chromatography (HSCCC) traditional Chinese medicines (TCM) |
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