The effect of anodal stimulation on V-V timing at varying V-V intervals |
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Authors: | van Gelder Berry M Bracke Frank A Meijer Albert |
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Institution: | Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands. carlgr@cze.nl |
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Abstract: | We studied the effect of anodal capture at the ring electrode of the right ventricular (RV) lead on interventricular (V-V) timing during biventricular (BiV) pacing, in which left ventricular (LV) pacing was preceding RV pacing. The V-V interval was programmed from 80 to 4 ms (LV first) in the LV unipolar (LV tip--generator can) followed by the LV tip-RV ring pacing configuration. In the LV unipolar configuration, V-V programming leads to a continuous change in morphology of the QRS complex according to a change in collision of both activation fronts. When using the LV tip-RV ring configuration with anodal capture at the RV ring electrode no change in QRS morphology was recorded varying the V-V interval from 80 to 60 and 40 ms. However, at V-V intervals between 20 and 4 ms a change in morphology of the QRS complex was recorded, which was due to additional cathodal stimulation of the RV tip electrode during RV stimulation. |
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Keywords: | V-V timing anodal stimulation cardiac resynchronization therapy |
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