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6种抗菌中药对耐甲氧西林金黄色葡萄球菌的抑菌作用
引用本文:闫小娟,张静玲,杨敬芳,骆鹏,张庶民,邱景富. 6种抗菌中药对耐甲氧西林金黄色葡萄球菌的抑菌作用[J]. 中国热带医学, 2009, 9(2): 219-220
作者姓名:闫小娟  张静玲  杨敬芳  骆鹏  张庶民  邱景富
作者单位:1. 重庆医科大学公共卫生学院,重庆,400016
2. 河北北方学院第二附属医院检验科,河北,张家口,075100
3. 中国药品生物制品鉴定所,北京,100050
基金项目:重庆医科大学公共卫生学院大学生科技创新基金资助
摘    要:目的观察几种常用抗菌中药对耐甲氧西林金黄色葡萄球菌(MRSA)的抑菌活性。方法选择6种(黄连、苦参、连翘、大黄、生地、知母)常用抗菌中药,采用水提法提取浓度至1g/ml。以稀释法测定上述中药对100株临床分离株的最低抑菌浓度(MIC)。结果大黄、黄连、连翅对MRSA有较强抑菌作用,其中以黄连对MRSA的作用最强,MIC值≤0.025g/ml。同一种中药对MRSA的不同菌株表现出相近的抑菌活性。结论常用抗菌中药对MRSA有一定的抑菌作用,在耐甲氧西林金黄色葡萄球菌感染的防治中抗菌中药可以发挥一定作用。

关 键 词:耐甲氧西林金黄色葡萄球菌  药物敏感试验  抗菌作用  最小抑菌浓度

Antibacteral effect of six traditional Chinese medicines against methicillin-resistant Staphylococcus aureu
YAN Xiao-juan,ZHANG Jing-ling,YANG Jing-fang,et al.. Antibacteral effect of six traditional Chinese medicines against methicillin-resistant Staphylococcus aureu[J]. China Tropical Medicine, 2009, 9(2): 219-220
Authors:YAN Xiao-juan  ZHANG Jing-ling  YANG Jing-fang  et al.
Affiliation:College of Public Health;Chongqing Medical University;Chongqing 400016;P.R.China
Abstract:Objective To investigate antibacterial activity of traditional Chinese medicine against methicillin-resisistant Staphylococcus aureu(MRSA).Methods Six traditional Chinese medicines(Coptis Chinesis etc) were selected and extracted with pure water to make a concoction of 1g/ml.100 clinicial isolated strains of MRSA were used to determine their minimal inhibitory concentration in vitro with liquid dilution method.Results Three herbs had inhibitory effects on the strain of MRSA with varied extent,among which Co...
Keywords:Traditional Chinese Medicine  Methicillin-resisistant Staphylococcus aureu  Antibacterial activity  Minimal inhibitory concentration  
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