| Susceptibility of Mixed Infection of Ureaplasma Urealyticum and Mycoplasma Hominis to Seven Antimicrobial Agents and Comparison with that of Ureaplasma Urealyticum Infection |
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| 作者姓名： | 黄长征 刘志香 林能兴 涂亚庭 李家文 张德美 |
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| 作者单位： | Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022，Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022，Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022，Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022，Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022，Department of Dermatology，Xiehe Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430022 |
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| 摘 要： | Summary:In order to investigate the susceptibility of mixed infection of Ureaplasma Urealyticum(UU)and Mycoplasma Hominis(MH)to 7 kinds of antimicrobial agents and comparison with thatof UU infection in NGU patients,the in vitro susceptibility was determined by using microdilutionmethod.The positive results were analyzed.The results showed that the sequence of susceptibility to7 kinds of antimicrobial agents for both UU infection group and UU-MH mixed infection group wasalmost the same from the highest susceptibility to the lowest accordingly:Josamycin,Doxycycline,Minocycline,Sparfloxacin,Roxithromycin,Ofloxacin and Azithromycin.The total drug resistancerate for UU-MH mixed infection group(97.67％)was significantly higher than that for UU infec-tion group(44.67％,P<0.01).The highest drug resistance rate in UU group and UU-MH mixedinfection group was 31.33％(Ofloxacin)and 90.48％(Azithromycin)respectively.UU-MHmixed infection showed an increased drug resistance and changes of drug resistance spectrum.
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Susceptibility of Mixed Infection of Ureaplasma Urealyticum and Mycoplasma Hominis to Seven Antimicrobial Agents and Comparison with that of Ureaplasma Urealyticum Infection |
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| HUANG Changzheng LIU Zhixiang LIN Nengxing TU Yating LI Jiawen ZHANG Demei.Susceptibility of Mixed Infection of Ureaplasma Urealyticum and Mycoplasma Hominis to Seven Antimicrobial Agents and Comparison with that of Ureaplasma Urealyticum Infection[J].Journal of Zuazhong University of Science and Technology: Medical Edition,2003,23(2). |
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| Authors: | HUANG Changzheng LIU Zhixiang LIN Nengxing TU Yating LI Jiawen ZHANG Demei |
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| Institution: | Department of Dermatology, Xiehe Hospital, Tong ji Medical College, Huazhong University of Science and Technology, Wuhan 430022 |
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| Abstract: | In order to investigate the susceptibility of mixed infection of Ureaplasma Urealyticum (UU) and Mycoplasma Hominis (MH) to 7 kinds of antimicrobial agents and comparison with that of UU infection in NGU patients, the in vitro susceptibility was determined by using microdilution method. The positive results were analyzed. The results showed that the sequence of susceptibility to 7 kinds of antimicrobial agents for both UU infection group and UU-MH mixed infection group was almost the same from the highest susceptibility to the lowest accordingly: Josamycin, Doxycycline, Minocycline, Sparfloxacin, Roxithromycin, Ofloxacin and Azithromycin. The total drug resistance rate for UU-MH mixed infection group (97. 67 %) was significantly higher than that for UU infection group (44. 67 %, P<.0. 01). The highest drug resistance rate in UU group and UU-MH mixed infection group was 31. 33 % (Ofloxacin) and 90. 48 % (Azithromycin) respectively. UU-MH mixed infection showed an increased drug resistance and changes of drug resistance spectrum. |
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| Keywords: | urea plasma urealyticum mycoplasma hominis drug susceptibility mixed infection antimicrobial agent |
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